CLARIFYING CAUSALITY AND INFORMATION FLOWS BETWEEN TIME SERIES: PARTICULATE AIR POLLUTION, TEMPERATURE, AND ELDERLY MORTALITY

Clarifying causality and information flows between time series: Particulate air pollution, temperature, and elderly mortality

Exposure-response associations between fine particulate matter (PM2.5) and mortality have been extensively studied but potential confounding by daily minimum and maximum temperatures in the weeks preceding death has not been carefully investigated.This paper seeks to close that gap by using lagged partial dependence plots (PDPs), sorted by importan

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Kinase Inhibitor Screening Identifies Cyclin-Dependent Kinases and Glycogen Synthase Kinase 3 as Potential Modulators of TDP-43 Cytosolic Accumulation during Cell Stress.

Abnormal processing of TAR DNA binding protein 43 (TDP-43) has been identified as a major factor in neuronal degeneration during amyotrophic lateral sclerosis (ALS) or frontotemporal lobar degeneration (FTLD).It is unclear how changes to TDP-43, including nuclear to cytosolic translocation and subsequent accumulation, are controlled in these diseas

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